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anti nav1 8  (Alomone Labs)


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    Structured Review

    Alomone Labs anti nav1 8
    Anti Nav1 8, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 95/100, based on 44 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/anti+nav1+8/Anti-NaV1%2E8+Antibody/10__1113_slash_jp290517-371-16-17
    Average 95 stars, based on 44 article reviews
    anti nav1 8 - by Bioz Stars, 2026-09
    95/100 stars

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    Related Articles

    Blocking Assay:

    Article Title: Over-expression of miR-3584-5p Represses Nav1.8 Channel Aggravating Neuropathic Pain caused by Chronic Constriction Injury.
    Article Snippet: Nav1.8, a tetrodotoxin-resistant voltage-gated sodium channels (VGSCs) subtype encoded by SCN10A, which plays an important role in the production and transmission of peripheral neuropathic pain signals.. Studies have shown that VGSCs may be key targets of MicroRNAs (miRNAs) in the regulation of neuropathic pain.. In our study, bioinformatics analysis showed that the targeting relationship between miR-3584-5p and Nav1.8 was the most closely.


    Article Title: Development of a 3-dimensional organotypic model with characteristics of peripheral sensory nerves
    Article Snippet: .. The samples were blocked in blocking buffer (PBS containing 0.1% Tween 20 and 3% BSA) for 1 h at room temperature, and then incubated for 24 h at room temperature with the following primary antibodies: mouse anti-NF200 (1:400, Sigma-Aldrich, #N0142, RRID: AB_477257 ), rabbit anti-CGRP (1:200, Sigma-Aldrich, #C8198, RRID: AB_259091 ), Isolectin B4 (Ib4)-FITC conjugate (1:250, Sigma-Aldrich, #L2895), rabbit anti-MBP (1:1000, Abcam, Cambridge, UK, #ab40390, RRID: AB_1141521 ), mouse anti-Caspr, clone K65/35 (1:100, Merck, Darmstadt, Germany, #MABN69, RRID: AB_10806491 ), rabbit anti-Ezrin (1:200, Cell Signaling Technology, Danvers, MA, USA, #3145, RRID: AB_2100309 ), mouse anti-Tubulin β3 (1:500, BioLegend, San Diego, CA, USA, #801201, RRID: AB_2313773 ), rabbit anti-Nav1.8 (1:200, Alomone labs, Jerusalem, Israel, #ASC-016-GP, RRID: AB_2040188 ), guinea pig anti-TRPV1 (1:200, Neuromics, Edina, MN, USA, #GP14100, RRID: AB_1624142 ), rabbit anti-TRPA1 (1:200, Novus Biologicals, Centennial, CO, USA, #NB110-40763, RRID: AB_715124 ), goat anti-TrkA (1:200, R&D systems, Minneapolis, MN, USA, #AF1056, RRID: AB_2283049 ), goat anti-TrkB (1:200, R&D systems, #AF1494, RRID: AB_2155264 ), rabbit anti-Npy2r (1:50, Sigma-Aldrich, #SAB4502029, RRID: AB_10747296 ), rabbit anti-GFAP (1:1000, Abcam, #ab7260, RRID: AB_305808 ), rabbit anti-S100β (1:1000, Abcam, #ab52642, RRID: AB_882426 ), rabbit anti-Iba1 (1:500, Fujifilm Wako Pure Chemical Industries, #019–19741, RRID: AB_839504 ), mouse anti-CD31 (1:500, Cell Signaling Technology, #3528, RRID: AB_2160882 ) or rabbit anti-ATF3 (1:200, Sigma-Aldrich, #HPA001562, RRID: AB_1078233 ). .. After washing three times with PBS, the samples were incubated for 3 h at room temperature with appropriate secondary antibodies conjugated with Alexa Fluor 594, 488 and/or 405 (1:200, Thermo Fisher Scientific).

    Incubation:

    Article Title: Over-expression of miR-3584-5p Represses Nav1.8 Channel Aggravating Neuropathic Pain caused by Chronic Constriction Injury.
    Article Snippet: Nav1.8, a tetrodotoxin-resistant voltage-gated sodium channels (VGSCs) subtype encoded by SCN10A, which plays an important role in the production and transmission of peripheral neuropathic pain signals.. Studies have shown that VGSCs may be key targets of MicroRNAs (miRNAs) in the regulation of neuropathic pain.. In our study, bioinformatics analysis showed that the targeting relationship between miR-3584-5p and Nav1.8 was the most closely.


    Article Title: Development of a 3-dimensional organotypic model with characteristics of peripheral sensory nerves
    Article Snippet: .. The samples were blocked in blocking buffer (PBS containing 0.1% Tween 20 and 3% BSA) for 1 h at room temperature, and then incubated for 24 h at room temperature with the following primary antibodies: mouse anti-NF200 (1:400, Sigma-Aldrich, #N0142, RRID: AB_477257 ), rabbit anti-CGRP (1:200, Sigma-Aldrich, #C8198, RRID: AB_259091 ), Isolectin B4 (Ib4)-FITC conjugate (1:250, Sigma-Aldrich, #L2895), rabbit anti-MBP (1:1000, Abcam, Cambridge, UK, #ab40390, RRID: AB_1141521 ), mouse anti-Caspr, clone K65/35 (1:100, Merck, Darmstadt, Germany, #MABN69, RRID: AB_10806491 ), rabbit anti-Ezrin (1:200, Cell Signaling Technology, Danvers, MA, USA, #3145, RRID: AB_2100309 ), mouse anti-Tubulin β3 (1:500, BioLegend, San Diego, CA, USA, #801201, RRID: AB_2313773 ), rabbit anti-Nav1.8 (1:200, Alomone labs, Jerusalem, Israel, #ASC-016-GP, RRID: AB_2040188 ), guinea pig anti-TRPV1 (1:200, Neuromics, Edina, MN, USA, #GP14100, RRID: AB_1624142 ), rabbit anti-TRPA1 (1:200, Novus Biologicals, Centennial, CO, USA, #NB110-40763, RRID: AB_715124 ), goat anti-TrkA (1:200, R&D systems, Minneapolis, MN, USA, #AF1056, RRID: AB_2283049 ), goat anti-TrkB (1:200, R&D systems, #AF1494, RRID: AB_2155264 ), rabbit anti-Npy2r (1:50, Sigma-Aldrich, #SAB4502029, RRID: AB_10747296 ), rabbit anti-GFAP (1:1000, Abcam, #ab7260, RRID: AB_305808 ), rabbit anti-S100β (1:1000, Abcam, #ab52642, RRID: AB_882426 ), rabbit anti-Iba1 (1:500, Fujifilm Wako Pure Chemical Industries, #019–19741, RRID: AB_839504 ), mouse anti-CD31 (1:500, Cell Signaling Technology, #3528, RRID: AB_2160882 ) or rabbit anti-ATF3 (1:200, Sigma-Aldrich, #HPA001562, RRID: AB_1078233 ). .. After washing three times with PBS, the samples were incubated for 3 h at room temperature with appropriate secondary antibodies conjugated with Alexa Fluor 594, 488 and/or 405 (1:200, Thermo Fisher Scientific).



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    Na V 1.8 antibody labels vestibular afferents and has three different patterns. (A) The heminodes of calyx‐only afferents ( green , color conventions are the same in all panels) are densely labeled with Na V 1.8‐like immunoreactivity ( red ), as seen in both longitudinal section (A) and (B) cross‐section of calyces labeled with calretinin. (C) Occasionally, the inner membrane of a calyx surrounding a type I hair cell, most likely belonging to a dimorphic afferent since these were found in the periphery, is labeled with Na V 1.8. However, because confocal lacks the resolution of electron microscopy, this could also be a type I hair cell membrane. In (D) Na V 1.8 is seen to label the calyx endings of calyces ( arrows ) with relatively light calretinin label (D’). Scale bars: A, C, D = 5 µm, B = 10 µm.
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    Na V 1.8 antibody labels vestibular afferents and has three different patterns. (A) The heminodes of calyx‐only afferents ( green , color conventions are the same in all panels) are densely labeled with Na V 1.8‐like immunoreactivity ( red ), as seen in both longitudinal section (A) and (B) cross‐section of calyces labeled with calretinin. (C) Occasionally, the inner membrane of a calyx surrounding a type I hair cell, most likely belonging to a dimorphic afferent since these were found in the periphery, is labeled with Na V 1.8. However, because confocal lacks the resolution of electron microscopy, this could also be a type I hair cell membrane. In (D) Na V 1.8 is seen to label the calyx endings of calyces ( arrows ) with relatively light calretinin label (D’). Scale bars: A, C, D = 5 µm, B = 10 µm.
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    Na V 1.8 antibody labels vestibular afferents and has three different patterns. (A) The heminodes of calyx‐only afferents ( green , color conventions are the same in all panels) are densely labeled with Na V 1.8‐like immunoreactivity ( red ), as seen in both longitudinal section (A) and (B) cross‐section of calyces labeled with calretinin. (C) Occasionally, the inner membrane of a calyx surrounding a type I hair cell, most likely belonging to a dimorphic afferent since these were found in the periphery, is labeled with Na V 1.8. However, because confocal lacks the resolution of electron microscopy, this could also be a type I hair cell membrane. In (D) Na V 1.8 is seen to label the calyx endings of calyces ( arrows ) with relatively light calretinin label (D’). Scale bars: A, C, D = 5 µm, B = 10 µm.
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    Na V 1.8 antibody labels vestibular afferents and has three different patterns. (A) The heminodes of calyx‐only afferents ( green , color conventions are the same in all panels) are densely labeled with Na V 1.8‐like immunoreactivity ( red ), as seen in both longitudinal section (A) and (B) cross‐section of calyces labeled with calretinin. (C) Occasionally, the inner membrane of a calyx surrounding a type I hair cell, most likely belonging to a dimorphic afferent since these were found in the periphery, is labeled with Na V 1.8. However, because confocal lacks the resolution of electron microscopy, this could also be a type I hair cell membrane. In (D) Na V 1.8 is seen to label the calyx endings of calyces ( arrows ) with relatively light calretinin label (D’). Scale bars: A, C, D = 5 µm, B = 10 µm.
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    Image Search Results


    Na V 1.8 antibody labels vestibular afferents and has three different patterns. (A) The heminodes of calyx‐only afferents ( green , color conventions are the same in all panels) are densely labeled with Na V 1.8‐like immunoreactivity ( red ), as seen in both longitudinal section (A) and (B) cross‐section of calyces labeled with calretinin. (C) Occasionally, the inner membrane of a calyx surrounding a type I hair cell, most likely belonging to a dimorphic afferent since these were found in the periphery, is labeled with Na V 1.8. However, because confocal lacks the resolution of electron microscopy, this could also be a type I hair cell membrane. In (D) Na V 1.8 is seen to label the calyx endings of calyces ( arrows ) with relatively light calretinin label (D’). Scale bars: A, C, D = 5 µm, B = 10 µm.

    Journal: The Journal of Comparative Neurology

    Article Title: Distribution of Voltage‐Gated Sodium Channels and Scaffolding Proteins on Vestibular Calyx Ending Delineates the Axon Initial Segment

    doi: 10.1002/cne.70127

    Figure Lengend Snippet: Na V 1.8 antibody labels vestibular afferents and has three different patterns. (A) The heminodes of calyx‐only afferents ( green , color conventions are the same in all panels) are densely labeled with Na V 1.8‐like immunoreactivity ( red ), as seen in both longitudinal section (A) and (B) cross‐section of calyces labeled with calretinin. (C) Occasionally, the inner membrane of a calyx surrounding a type I hair cell, most likely belonging to a dimorphic afferent since these were found in the periphery, is labeled with Na V 1.8. However, because confocal lacks the resolution of electron microscopy, this could also be a type I hair cell membrane. In (D) Na V 1.8 is seen to label the calyx endings of calyces ( arrows ) with relatively light calretinin label (D’). Scale bars: A, C, D = 5 µm, B = 10 µm.

    Article Snippet: Na V 1.8 , NeuroMab , 75‐166 RRID:AB_2183861 , , , , X , , Datasheet.

    Techniques: Labeling, Membrane, Electron Microscopy